Recombinant human lactoferrin induces apoptosis, disruption of F-actin structure and cell cycle arrest with selective cytotoxicity on human triple negative breast cancer cells. Apoptosis.
重組人乳鐵蛋白誘導細胞凋亡、F-肌動蛋白結構的破壞和細胞週期停滯,對人三陰性乳腺癌細胞具有選擇性細胞毒性。細胞凋亡。
Killing of Gram-negative Bacteria by Lactofernn and Lysozyme
乳鐵蛋白和溶菌酶殺滅革蘭氏陰性菌
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Lactofernn is an immunomodulatory human protein expressed throughout the body and found in highest concentrations in milk and colostrums.
乳鐵蛋白是一種免疫調節性人類蛋白質,在全身表達,在牛奶和初乳中濃度最高。
Lactoferricin, a peptide derived from lactoferrin has also demonstrated increased apoptosis via the intrinsic pathway in leukemic and breast carcinoma cells by activating caspases-3 and -9 [45, 46].
乳鐵蛋白,一種衍生自乳鐵蛋白的肽,也通過激活 caspase-3 和 -9,通過白血病和乳腺癌細胞的內在途徑增加了細胞凋亡 [45, 46]。
Bovine Milk Lactoferrin Selectively Kills Highly Metastatic Prostate Cancer PC-3 and Osteosarcoma MG-63 Cells In Vitro
牛乳乳鐵蛋白在體外選擇性殺死高度轉移性前列腺癌 PC-3 和骨肉瘤 MG-63 細胞
lactoferrin + linolenic acid combination inhibited HT29 tumor formation
乳鐵蛋白+亞麻酸組合抑制HT29腫瘤形成
Bovine lactoferrin and lactoferricin exert antitumor activities on human colorectal cancer cells (HT-29) by activating various signaling pathways
牛乳鐵蛋白和乳鐵蛋白通過激活多種信號通路對人結直腸癌細胞(HT-29)發揮抗腫瘤活性
Lactoferrin (Lf) is an iron-binding glycoprotein that is present at high concentrations in milk.
乳鐵蛋白 (Lf) 是一種鐵結合糖蛋白,以高濃度存在於牛奶中。
Bovine lactoferricin (LfcinB) is a peptide fragment generated by pepsin proteolysis of bovine lactoferrin (bLf).
牛乳鐵蛋白 (LfcinB) 是由牛乳鐵蛋白 (bLf) 的胃蛋白酶蛋白水解產生的肽片段。
Immunoblotting results confirmed that both bLf and LfcinBs increased expression of caspase-8, p53, and p21, critical proteins in tumor suppression.
免疫印跡結果證實 bLf 和 LfcinBs 都增加了 caspase-8、p53 和 p21 的表達,這些蛋白質是腫瘤抑制中的關鍵蛋白。
Lactoferrin also has the capacity to induce apoptosis and inhibit proliferation in cancer cells
乳鐵蛋白還具有誘導細胞凋亡和抑制癌細胞增殖的能力
小結:
全套治療所有癌症的食材參考Part-IX(治療癌症食療的全貌逐漸明朗邁向尾聲~~~)
告訴我們:
干擾素-γ(IFN-γ)跟細胞凋亡的起始Caspase-2,-8,-9上調有關,也跟細胞凋亡的最終執行caspases-3,-6,-7有關
總結以上:
建議喝鮮奶或優酪乳抗癌及預防癌細胞發生。